Correlation between Hepatitis B Viral Load and Liver Function Test among Hepatitis B Virus Patients in Khartoum State, Sudan

المؤلفون

  • Sawsan A. A. Altom Tropical Disease TeachingHospital, Omdurman, Sudan.
  • Abdelsalam MA Nail Tropical Disease Teaching Hospital, Omdurman, Sudan;Omdurman Islamic University, Faculty of Medicine and Health Sciences, Department of Internal Medicine, Omdurman, Sudan
  • Ahmed Mudawi Musa University of Khartoum, Institute of Endemic Diseases, Khartoum, Sudan.
  • Gad Allah Modawe Omdurman Islamic University, Faculty of Medicine and Health Sciences, Department of Biochemistry, Omdurman, Sudan

DOI:

https://doi.org/10.37375/sjms.v2i2.2539

الكلمات المفتاحية:

hepatitis B، viral load، inflammation، hepatology

الملخص

Hepatitis B virus (HBV) infection is a global public health problem. Sudan is classified among the countries with high hepatitis B virus seroprevalence . The purpose of this study was to study the correlation between the hepatitis B viral load and the liver function test in hepatitis BV patients  Descriptive cross-sectional hospital based study conducted at the hepatology clinic Ibn Sinaa teaching hospital, covering all the patients who presented to the clinic  from March-April  2018, primary data was collected from the patients and/or their care giver, a specifically designed questionnaire was used, and then the data was re-entered into a predesigned data collection form. A P value of 0.05 or less was considered statistically significant. The Data was analyzed using  Social Package Statistical  Analysis version (24). A total of 83 patients, 19 (22.9%) have viral load level less than 20 IU\ml, 33(39.8%) have viral ranging between (20-2000IU\ ML ), 13 (15.6%)have viral  load between (2000-20,000IU\ML ) and 18(21.7%)have viral  load more than 20,000IU\ML ) . The study showed a significant correlation between hepatitis B viral load and alanine aminotransferase level (ALT) with a P value of 0.027. The study showed a significant correlation between hepatitis B viral load and aspartate aminotransferase level (AST) with a P value of 0.009 .The study also showed there was a significant relation between hepatitis B viral load and serum albumin level with a P  value of 0.007. Hepatitis B viral load was not affected by the age, gender or the duration of the disease. The liver function tests is recommended to be used as an indicator for the hepatitis B viral load and the  degree of liver inflammation. 

المراجع

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التنزيلات

منشور

2023-12-27

كيفية الاقتباس

Sawsan A. A. Altom, Abdelsalam MA Nail, Ahmed Mudawi Musa, & Gad Allah Modawe. (2023). Correlation between Hepatitis B Viral Load and Liver Function Test among Hepatitis B Virus Patients in Khartoum State, Sudan. Sirte Journal of Medical Sciences, 2(2), 8–15. https://doi.org/10.37375/sjms.v2i2.2539