Sirte Journal of Medical Sciences

Routine blood tests as a crucial diagnostic tool for COVID-19

Khdija Suleman Mohamed — 2024-07-01

Routine laboratory tests are essential for identifying COVID-19 cases. Reviewing the clinical features of confirmed COVID-19 cases retrospectively can offer valuable insights, the data were collected from 240 files, which included all files from the beginning of the opening of the isolation center in first of June 2020, until the 30^th of December 2021. Of the 240 cases, 100 cases were dead. Of survived cases, 54% were male and 46% were female. While the dead cases, 56% were male and 44% were female. In conclusion, the blood cell count plays a crucial role in both diagnosing and predicting the outcome of COVID-19, serving as a routine diagnostic tool. Low levels of leukocytes and differential white blood cell count can serve as indicators of a COVID-19 infection, while higher counts may indicate the progression of the disease. Conversely, lymphocyte and D-dimer levels do not provide diagnostic value but are indicative of the severity of COVID-19 cases.

In-hospital cardiac arrest epidemiology and intervention

Ali Ismaeil — 2024-06-30

Introduction: Sudden cardiac arrest (SCA) is the abrupt loss of all cardiac activities as a result of acute heart rhythm disturbance and cessation of respiration, it is the most critical condition that faces any healthcare system, and that requires accurate precise coordinated intervention to achieve a favourable outcome. The epidemiological figures and the survival rates of in-hospital cardiac arrest vary significantly between developed and developing countries owing to the availability of rapid response resuscitation teams and advanced healthcare facilities. This study dictated to examine the epidemiology and the intervention aspects of in-hospital cardiac arrest in the city of Sirte at Ibn Sina Teaching Hospital. Methods: This study is a cross-sectional survey, dedicated to examining the epidemiological and intervention data of in-hospital cardiac arrest at IBN SENA TEACHING HOSPITAL in the city of Sirte, used a data collection form that included details of interest, a total of 591 files for patients who were admitted to the intensive care unit during the study period, 50 cases of cardiac arrest were registered and included in this study for analysis. Results: a total of 50 cases, with an overall incidence of 5.4 cardiac arrests for every 1000 admissions. males were arrested more than females during the study period; 66% males (34 cases) and 32% females (16 cases), the age group that has the highest frequency of cardiac arrest was (>75 years old) group for both sexes, and almost all of the registered cases were in the ICU, even though only 23 cases 46% were resuscitated, respiratory system diseases were the most frequent aetiology for cardiac arrest during the study period, followed by trauma and came 3rd the cardiovascular system diseases, Concomitant comorbidity of HTN and DM represents the most frequent pre-arrest illnesses which, and finally the survival rates were zero. Very important data were missed/undocumented that could improve the survival rates in one way or the other

Mortality Rate in the Neonatal Intensive Care Unit at IBN SINA Teaching Hospital Sirte-Libya

Muammar Makhlouf — 2024-06-30

Studying the mortality rate of newborns in the neonatal intensive care unit (NICU) is of paramount importance as it provides valuable insights into the effectiveness of medical interventions, clinical practices, and healthcare strategies aimed at reducing infant mortality. By analyzing the mortality data, healthcare professionals can identify areas for improvement, implement evidence-based practices, and develop targeted interventions to enhance the quality of care and ultimately save more infant lives, throughout one. Total number of newborns in hospital 4,369 number of death 44. The data focused on death certificates of neonates

Optimizing Dental Implant Outcomes: A Comprehensive Approach to Preventing and Managing Peri-Implantitis

Malek A. Abdulmatlob — 2024-06-30

Background: Peri-implantitis, a progressive inflammatory condition affecting dental implants, poses a significant threat to the long-term success of implant therapy. This study aimed to develop a comprehensive protocol for the prevention and management of peri-implantitis, integrating various preventive and therapeutic interventions. Methods: A multi-center, prospective, randomized controlled trial was conducted, involving 492 participants randomly assigned to five study groups: control, preventive intervention 1 (surface modification), preventive intervention 2 (patient education), therapeutic intervention 1 (regenerative techniques), and therapeutic intervention 2 (adjunctive antimicrobial therapies). Clinical assessments, including periodontal parameters, marginal bone levels, and patient-reported outcomes, were evaluated over a 5-year follow-up period. Results: All intervention groups showed significantly greater improvements in periodontal parameters, marginal bone levels, and patient-reported outcomes compared to the control group (p < 0.05). The therapeutic intervention group 1 (regenerative techniques) demonstrated the most favorable outcomes, with the greatest reductions in probing depth, clinical attachment level, bleeding on probing, and plaque index, as well as the smallest marginal bone loss and highest implant survival rate (94.2%). Participants in this group also reported the highest oral health-related quality of life, lowest pain and discomfort levels, and highest satisfaction with treatment outcomes. Conclusion: The findings highlight the efficacy of various preventive and therapeutic interventions in optimizing dental implant outcomes and improving patient quality of life. The multidisciplinary approach adopted in this study contributed to the development of a comprehensive protocol for the prevention and management of peri-implantitis, integrating cutting-edge research and evidence-based practices

Evaluation of Hematological Changes in The Pregnant Women in EL-Beyda City- Libya

Najat M. H. Mohammed — 2024-06-30

Background: Pregnant women normally undergo to several hematological changes perhaps anemia is considered the significant one. It is a major public health problem and commonly associated with many consequences as low birth weight, premature delivery and the increased risk of the maternal mortality and morbidity in the pregnant women, mainly in the developing countries

.The aim of the study: The present study was designed to estimate the changes in hematological parameters in women during pregnancy at EL-Beyda City. Methods: Cross sectional study involved 350 randomly selected pregnant mothers who are attended several medical clinics in the period of February to July 2022, of age group 17-48 years. A venous blood samples were collected in EDTA tubes and analyzed for complete blood counts (CBC) to evaluate hemoglobin levels (Hb), mean cell volume (MCV), mean cell hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), white blood cells (WBCs) and platelets count. Other data were also reported including women age, trimester of pregnancy, the number of the gravida and the parity. Results were obtained by analyzing collected data by SPSS version 26 and represented as mean ± SE and P value is considered significant when it is less than 0.05. The Results: The mean age of the participants women was 29.5(±0.33), the overall prevalence of anemia was 57% and vast of them were in third trimester period. Out of 204 anemic women, 109 (53.4%) of them had normocytic normochromic anemia (mean of MCV 88fl). while the rest 94 (46%) were suffered microcytic hypochromic anemia (mean of MCV 72fl). The present investigation was revealed that the mean of hemoglobin of anemic women was 9.84±0.06. which are significantly different in the mean of non-anemic women (p value =0.000) as well as majority of women 165 (81 %) had mild anemia (Hb= 9-10.9 g/dl).

Conclusion: We can conclude that the prevalence of anemia in Libya in the studied population is considerably high in comparison to other countries, therefore the great awareness efforts are recommended to encourage a regular antenatal checkups

Estimation of Plasma Triglyceride Level among Patients with Diabetes Mellitus, Wad Medani, Gezira State, Sudan, in 2022

GadAllah Modawe — 2024-06-30

Background: In Sudan and around the world, Diabetes Mellitus is a growing health concern. It is a serious, ongoing condition. The Middle East and North Africa area (MENA) area, which includes Sudan, has the world's highest prevalence of diabetes. It was predicted to be about 25%. More concerning is the prediction that by 2030.

Patients and Methods: This is a case control study conducted in Aldaraga Health Center for Diabetes Care and Wad Medani Pediatric Teaching Hospital, Wad Medani, Gezira State, Sudan to estimate the plasma triglyceride level among diabetic patients. A total of 160 participants were included in the study, ninety patients were case group (Diabetic patients), their mean age was (40.90±24.00) years and seventy were control group (Healthy individuals) their mean age was (45.78±22.38) years. Among case, 37 (41%) were males while 53 (59%) were females. Data were collected by using questionnaire and analyzed by computer program SPSS (Version 20). After fasting (8-12) hours, 2 ml of heparinized plasma and 1.5 ml EDTA whole blood was collected for estimation of triglyceride and HbA1c respectively and then plasma was stored at -200C till assay was done by Cobas C 311.

Results: It revealed high rate of poor glycemic control in Sudanese diabetic patients (81%). There were significance differences in plasma triglyceride between diabetic patients and control group (P value =0.002), age groups (P value =0.000), and gender (P value =0.019). However, there were no statistically significant differences when compared plasma triglyceride levels with glycosylated hemoglobin and duration of the disease (P values = 0.514 and 0.096 respectively).

Conclusion: Diabetes, age, and gender, but not glycosylated hemoglobin or disease duration, were found to have an impact on triglyceride levels in this study.

Risks of Ovarian, Breast, and Uterine Corpus Cancer in Women Receiving IVF Treatment

Muna Elgobbi — 2024-06-30

Background A common treatment for infertility or genetic issues today is assisted reproductive technology (ART), which includes in vitro fertilization (IVF). Numerous studies have been done in this area in order to better understand the potential effects of this technique on women who undergo in vitro fertilization (IVF) and children born through IVF. This study is an updated meta-analysis to determine whether there is a causal relationship between different fertility treatments and ovarian, breast cancer. - Methods To reflect contemporary in vitro fertilization (IVF) practice, studies written during the last 20 years were included. Finding out whether women who receive hormonal reproductive treatment have an elevated risk of ovarian, breast cancer was the study's main objective. To find out if individual fertility therapies increased the risk of breast cancer, one of the secondary outcomes was to do so. Researcher observed first cancer diagnoses for ovarian, breast, and corpus uteri were compared to expected rates for each age, sex, and period. With the help of age, sex, and time-specific incidence rates, standardized incidence ratios (SIRs) were computed. Results On this subject, there are opposing viewpoints. According to some research, the risk of developing hormone-sensitive malignancies, such as ovarian, breast cancer, has somewhat increased. Breast cancer is one of the most common malignancies in women and the long-term use of IVF drugs can raise estrogen hormones and lead to excessive gene expression, increasing the risk of the disease. Conclusion There are a few dangers to be aware of as a result of the theory that lengthy IVF treatments may cause breast cancer in IVF candidates. Additionally, ovarian, breast cancer risk may be elevated in women with a favorable family history and associated inherited genes. The likely effects of the reproductive therapy approaches should therefore be explained to women who are candidates for IVF. Explained to women who are candidates for IVF.