Sirte Journal of Medical Sciences <p><strong></strong></p> <p><strong>Sirte University Journal of Medical Sciences, a semi-annual refereed medical journal specialized in publishing research and scientific articles in the field of Medicine, Dentistry and Health sciences. It was established by a decision of the University President No. (12) For the year 2021 on 04/05/2021, and the Journal obtained the legal deposit number (991/ 2021) from the National Library.</strong></p> <p><strong>Through the journal, scientific medical research is published, which aims to see the latest medical research and studies and how to deal with diseases and causes, treat them and limit their spread.</strong></p> <p><strong>The Journal targets specialists and specialists in the field of medical and allied sciences to include all medical fields in medicine, dentistry, nursing, applied medical sciences, pharmacy and public health, in addition to researchers in the field of medical sciences.</strong></p> <p><strong>The journal is pleased to invite all researchers to publish their scientific research in it to enrich scientific research in the field of medical sciences.</strong></p> en-US (Prof Dr. Abdallah Mohamed Alhwal) (Mahmoud Albarq) Fri, 30 Jun 2023 00:00:00 +0000 OJS 60 Prevalence of Diabetes and Hypertension amongst patients admitted with Acute Myocardial Infarction to Ibn-Sina Teaching Hospital <p>Coronary heart disease (CHD) is a leading cause of morbidity and mortality worldwide. Acute Myocardial Infarction (AMI) is the most common form of CHD and is responsible for over 15% of mortality every year. Hypertension (HTN) and diabetes mellitus (DM) are thought to be the most significant risk factors for developing CHD. Old age is a risk factor in both genders. However, Younger female are less likely to be affected compared to males. This study aims to assess the prevalence of HTN, DM, or both amongst patients admitted with acute MI (AMI) and to demonstrate the distribution of AMI according to age group and gender. Comorbidity data from 36 patients (22 males and 14 females) admitted with AMI to Ibn-Sina hospital between January 2018 and December 2018 was analyzed, tabulated, and graphed using Microsoft Excel.Our results showed that 8 patients (22.2%) had HTN prior to admission and 6 patients (16.6%) had DM, whilst 16 patients (44.4%) had both HTN and DM. 6 patients (16.6%) had neither HTN or DM. Male patients had the highest incidence of AMIs (22 patients, 62.5%). Furthermore, the highest incidence of AMIs in male patients were in the ‘40-59’ age group, as compared with the female group with the highest incidence of AMIs being in the ‘60-69’ age group. A combined co-morbidity of HTN and DM was shown to be a high-risk factor for the incidence of MI.&nbsp; Furthermore, MI incidence was shown to be higher in the male population, and presents at a younger age in males than females.</p> Hend Masoud, Aisha Ali Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Surgical Management of Camptodactyly <p>Camptodactyly is a congenital deformity characterized by a flexed posture in the proximal interphalangeal joint. It is generally found in the little finger and may or may not include the other fingers. It is painless and nontraumatic [1]. It affects approximately 1% of the population. It is bilateral in around two thirds of the patients, although the degree of contracture is usually not symmetrical [2]. The deformity generally increases during growth spurts, especially during the periods of rapid growth from one to four years and from 10 to 14 years of age [3]. The primary cause of this deformity is still a matter for discussion and there is no consensus in the worldwide literature. Although some cases occur sporadically, there is often an autosomal inheritance pattern present. The metacarpophalangeal and distal interphalangeal joints are unaffected, although they may develop compensatory deformities [4].&nbsp; The purpose of&nbsp; this study is to assess the clinical result of surgical treatment in management of&nbsp; camptadoctyly&nbsp; and to evaluate the results by&nbsp; clinical assessment. This retrospective study was carried out on fifteen patients. These patients with flexion deformity were admitted in Upper Limb and Reconstructive Microsurgery Unite in Assiut University Hospital and were managed by surgical treatment. Age ranges from 2to 15 year, the mean age intervention was 9.8 years.&nbsp; There were 9 males and 6 females as males 60% to 40% females, there were 4 cases with positive family history and 11 case with negative family history. And 4 cases with excellent result, 4 cases good ,7 cases with fair ,17 cases with poor result. From this study the best time to operative at age between (1.5-2.5) years. Also need more family knowledge about camptodactyly to start treatment early</p> Osama Muftah Aloud, Amr Alsayed Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Clinical and pathological factors predictive of response to neoadjuvant chemotherapy in Locally Advanced breast cancer <p>This study was performed to examine the predictive factors of pathologic complete response (pCR) in locally advanced breast cancer (LABC) patients after neoadjuvant chemotherapy (NAC). LABC remains a clinical challenge, as distant metastasis develops in most patients, and they will experience disease relapse and eventual death. The identification of reliable predictive factors for neoadjuvant chemotherapy in LABC would help select those patients most likely to benefit from neoadjuvant chemotherapy. 84 LABC Egyptian patients with neoadjuvant therapy regimens containing 3-6 cycles of anthracyclin-based chemotherapy, followed by modified radical mastectomy (MRM) and node dissections, followed by adjuvant hormonal therapy and Radiotherapy.The patients were divided into two groups: pathological complete response (pCR) or non-pCR group. Clinico-pathological characteristics were compared and analyzed, and multivariate analyses were performed to detect the predictive factors of pCR. The pCR rate in both the breast and axilla was (8.33%), and 91.67% of the patients showed partial response. Multivariate logistic regression demonstrated that pCR was significantly associated with The absence of nodal metastasis, necrosis, lymphovascular invasion and carcinoma in situ and negative ER , PR and HER2 and the non-triple negative tumours. the absence of tumor necrosis, DCIS and LVI and negative hormonal status on initial core biopsy are linked to achieving pCR</p> Aliyah Mohammad Salih, Asma Aboubakr Abdalraziq, Raba M. Abdalkarim Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Burr-hole versus Mini-craniotomy and (fenestration) membranectomy in management of membranous forming CSDH - Sirte experience <p>Objective: The best way to treat (membranous forming) chronic subdural hematoma is unknown. Thus, the purpose of this study was to compare single burr-hole drainage with mini-craniotomy in the treatment of (membrane forming) chronic subdural hematoma, taking into account complication and recurrence rates. Method: (7) patients with (membrane forming) CSDH who underwent surgery between January 2018 and June 2022 had their clinical and radiologic records extracted. They account for 2,5% of all CSDH patients (18) treated during the same time period. The cases undergoing various types of surgery were compared in terms of clinical and radiological outcomes. Result: These (7) patients were divided into two groups: group A (4) patients underwent a single burr-hole trepanation, (3) patients underwent mini-craniotomy and (fenestration) membraneotomy, during all procedures, subdural drainage was placed and removed three days later. All patients recovered completely, with only one case in group A having a rest subdural collection and no complications in group B .Conclusion: When compared to burr-hole evacuation, the mini-craniotomy with (fenestration) membraneotomy technique may be superior for the treatment of (membranous forming) CSDH. More subdural space visibility is made possible by the mini-craniotomy, which also enables more aggressive fluid evacuation, better irrigation of the area, the safe fenestration of any membranes that are accessible. Despite the evident limitations of this study, an upcoming effort to evaluate this technique may be merited</p> Hussain M. Amaigil, Aisha A. Abdelsalam, Abdalmanam Almabsoot Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Clinical pattern of psoriasis in patients seen at our private clinic, in Aden, Yemen <p>Background: Psoriasis is a chronic immune-mediated systemic disease that is influenced by genetic and environmental factors. &nbsp;Objective: To presents the demographic characteristics, and clinical variants of psoriatic patients. &nbsp;Materials and methods:&nbsp; Present work was a retrospective and observational study, conducted in patients of a private clinic of dermatology, in Almansoora, Aden, Yemen. All patients who attended the clinic during the period January 2018 to December 2021 and were diagnosed as psoriasis patients were included in this study.&nbsp;&nbsp; Data were collected and entered in a computer, and analyzed by using SPSS version 17. Results: The study patients were 168. They were (57.1%) males and (42.9%) females, with a male-to-female ratio of 1.3:1. The age of the patients ranged between 10 to 58 years. The mean age of the patients was 38.2 ± 12.6 years. The age group 41 – 50 had the highest number of patients 54 (32.1%), followed by the age group 31 – 40 years 40 (23.8%) years. The mean duration since the onset of the disease is 6.1 ± 4.6 years. The most common psoriasis type was plaque psoriasis (vulgaris) (65.4%). Family history related to psoriasis was positive among (20.2%) patients.&nbsp;&nbsp;&nbsp; Diabetes mellitus and hypertriglyceridemia were found equally among the study patients, each one in (9.5%) and arterial hypertension was found in (7.2%) patients. The involvement of nails was observed in (31%) of patients and Koebner phenomena was found in (23.8%) of patients. Conclusion: Psoriasis is predominant in male patients, with a male-to-female ratio of 1.3:1, and the most common psoriasis type was plaque psoriasis.</p> Amer Omer Bin Al-Zou Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Common Eye Diseases in children attending Makkah eye hospital in Aden, Yemen <p>Background: Eye diseases in children are important cause of medical consultation. This study aimed to determine the distribution and spectrum of childhood eye diseases at the pediatric outpatient clinics of Makkah eye hospital in Aden. Materials and method:This is an observational retrospective study. The medical records of all patients aged 16 years or younger who were seen at the pediatric ophthalmology outpatient clinics during the year 2021, were reviewed. The following data were recorded for each patient: sex, age, residency, site of trauma, site of disease, and diagnosis. Descriptive statistics were computed for continuous and categorical variables. The statistics computed included mean and standard deviations (SD) of continuous variables and are presented as mean ± SD, frequencies and percentages of categorical factors. Results: Total study patients were 146 (males were 61.6% and females were 38.4%). Most of them 58.2% were from rural areas. Their age ranged between 1 month to 16 years and their mean age was 7.1 ± 4.1 years. Children aged ≤ 5 years were (37.7%), of the age group 6 – 10 years were (35.6%) and of the age group 11 and 16 years were (26.7%). The most common eye disorders were ocular trauma in (43.2%) children. Squint was the second commonest disease and accounted (14.4%). Congenital glaucoma found in (11.6%) children, refractive error found in (9.6%) patients, and congenital cataract in (6.9%) children. Ocular trauma was predominant (19.9%) in the age group 6-10 years, while squint was predominant (6.8%) in the age group 10-16 years old and congenital glaucoma was predominant (10.2%) in the age group ≤ 5years. The highest frequency of refractive errors were found in children aged between 6 to 10 years and children aged between 11 to 16 years, (P = 0.000). Conclusion: The most common eye diseases in our study were ocular injuries, squint, congenital glaucoma, refractive errors and congenital cataract, respectively.</p> Reem Alkhadher Saleh, Ibtihal Aidroos Zain Gaffer Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Influence of preoperative factors on the outcome of root canal treatment (Part 1): A retrospective clinical study <p>Aim: The aim of this study was to evaluate the effect of preoperative prognostic variables (Gender, Age, General medical health, Tooth type, Tooth location, Pulpal and periapical status) on the outcome of the initial endodontic therapy. Material and methods: Ninety-one patients out of 109 were included and had complete medical and dental record. A total of 146 teeth received an endodontic treatment and overall 408 Canals obturated. All treatments were performed through 2018 and 2019, in a private Dental Clinic in Sirte, Libya. Two independent endodontists, who have analyzed all preoperative and postoperative radiographs. Treatment effectiveness was evaluated using the European Society of Endodontology's standards. The periapical index was used to grade the periapical state. Setting the level of significance at p ˂ 5% by applying chisquare Pearson test. Results: The initial root canal procedure had an overall success rate of 89.7%. The health status showed their power effect on success rate with 83.6% (p-value =0.0001). Periapical status had a strong effect on the outcome. Apical periodontitis (AP) was existing in 49 of all teeth, with a PAI &gt;3 in 17 teeth. The success rate (SR) was 61.6%, 11.6%, 6.8% &amp; 9.7% with teeth has PAI 1, PAI 2, PAI 3 and PAI &gt;3, respectively (p-value = 0.004). However, pulpal status shows that the success rate for vital teeth was 57.5% and for nonvital teeth was 32.2%.Conclusion: Within the parameters of the investigation, medical health and periapical condition have demonstrated to be powerful significant outcome predictors</p> Gazala Ehtiba, Ali Ehtiba Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000 Prevalence of urinary tract infection among HIV patients attending the infectious disease hospital in Benghazi, Libya <p>People living with Human Immunodeficiency Virus (HIV) are prone to opportunistic infections including urinary tract infection (UTI). There is limited evidence in Libya regarding UTIs and HIV. This study was conducted to determine the prevalence of UTI among HIV patients attending the infectious disease hospital in Benghazi, Libya.&nbsp; Urine samples are collected and processed by macroscopic and microscopic examination for the identification of bacteria. Antibiotic susceptibility testing was performed using Kirby-Bauer’s disc diffusion method. Urine samples were collected from 112 HIV seropositive patients, and 428 seronegative control group individuals.&nbsp; Out of 112 seropositive patients, 18(16%) had UTI. Escherichia coli was the most frequently occurring bacterial isolate 8(44%), followed by Staphylococcus aureus 4(21%), and Klebsiella species 3(17%). While the least common pathogens were Salmonella Species, Micrococcus, and Sphingo-bacterium; each had 1(6%). The age group 23-28 years recorded the highest prevalence of UTIs 11 (61%), while those aged 35-42 years had the least occurrence 2 (11%). On the other hand, out of 428 seronegative individuals' samples, 40(9%) yielded growth of bacteria. The distribution of uro-pathogens from urine specimens of seronegative patients revealed also Escherichia coli as the most prevalent uro-pathogens 18(45%), followed by Klebsiella species 8(20%) and then Staphylococcus aureus and Enterobacter species; each 5(12.5%). While the least common pathogens were Pseudomonas species and Staphylococcus Saprophyticus 2(5%). The age group 25-30 years recorded the highest prevalence of UTI; 11 (61%) in HIV-positive patients, while the age group. 41-70 years recorded the highest prevalence of UTI 18(45%) in HIV-negative patients. Female individuals showed the highest number of bacterial isolates; females had a prevalence of 14(78%) and males 4(22%) in seropositive patients, while in the seronegative patients, females had 35(87.5%) and males had 5(12.5). The study showed a high prevalence of UTIs among HIV patients which is an indication of the ineffectiveness of prophylaxis administered to HIV patients to prevent opportunistic</p> Salwa M Alfituri, Aisha M Alfituri Copyright (c) 2023 Fri, 30 Jun 2023 00:00:00 +0000