Mixed Ligand Complexes: Synthesis and Characterization Studies
DOI:
https://doi.org/10.37375/foej.v2i1.553Keywords:
Keywords: Schiff base, mixed ligand complexes and physiochemical characterization.Abstract
The synthesis and structural characterization of mixed ligand complexes of Schiff base derived from the condensation of 2-hydroxyacetophenone and 2,4-dinitrophenylhydrazine (HL1) and 2-aminophenol(L2) are reported. The ligands and their mixed ligand complexes were characterized on the bases of their IR, 1HNMR, UV-Vis, elemental analyses, magnetic moment and molar conductance measureents. The mixed ligand complexes under investigation were formed in the 1:1:1 or 1:1:2 [M:L1:L2] ratio as found from the elemental analysis data and found to have the formulae [L1ML2(H2O)2], where M = Mn(II), Fe(III), Co(II) and Ni(II) ions and [L1Cr(L2)2], The molar conductance results revealed that the complexes are non-electrolytes. IR spectra showed that the ligands are coordinated to the metal ions in a bidentate manner with donor sites. Magnetic moments are used to infer the coordinating capacity of the ligands and the geometrical structure of their complexes are found to be an octahedral.
References
Abou Melha, K. , "Antimicrobial, spectral, magnetic and thermal studies of Cu(II), Ni(II), Co(II), UO2(VI) and Fe(III) complexes of the Schiff base derived from Oxalylhydrazide", Journal of Enzyme Inhibition and Medicinal Chemistry, 23(2), 285–295(2008). DOI: 10.1080/14756360701448073.
Abd El-Halim, H. F., Mohamed, G. G., & Khalil, E. A. M, Synthesis, spectral, thermal and biological studies of mixed ligand complexes with newly prepared Schiff base and 1,10-phenanthroline ligands, Journal of Molecular Structure, 1146, 153-163(2017). DOI.org/10.1016/j.molstruc.2017.05.092.
Ahmad, W., Khan, S. A., Munawar, K. S., Khalid, A. & Kawan, S. "Synthesis, characterization and pharmacological evaluation of mixed ligand-metal complexes containing omeprazole and 8-hydroxyquinoline, Tropical Journal of Pharmaceutical Research,16(5), 1137-1146(2017). DOI.org/10.4314/tjpr.v16i5.23
Adalikwu, S. A., Offiong, O. E., Eno, E. A., & Ufefe, A. L. "Synthesis and spectral characterization of mixed ligand complexes derived from N-propylidene-2- metylpyridylamine and terpyridine", Global Journal of Pure and Applied Science, 17(4),523-527(2011).
Al- Mukhtar S., Hiba E., Al-Katib F., Al-Nuaimy L. A. "Preparation and characterization of some transition metal complexes with crotylxanthate ligand and their adducts with nitrogen bases", Raf. J. Sci., 26(1), 49-55(2017).
Benerjee A. & Chattopadhyay S., Review:"Synthesis and characterizationof mixed valence cobalt(III)/cobalt(II) complexes with N,O-donor Schiff base ligands", Polyhedron, 159(1), 1-11(2019).
Chauhan, G.R., Kharadi, G.J. & K.D. Patel, "Synthesis, spectroscopic and in-vitro antifungal studies of drug based mixed ligand complexes, Oriental Journal of Chemistry, 26(4), 1431-1436 (2010).
Derebe, M.G., Raju, V.J.T. & Retta, N. "Synthesis and characterization of some metal complexes of a Schiff base derived from ninhydrin and ,L-alanine", Bull. Chem. Soc. Ethiop., 16, 53–64(2002).
El-ajaily, M. M., Maihub, A. A., Mahanta, U. K., Badhei, G., Mohapatra, R. K. & Das, P. K. "mixed ligand complexes containing Schiff bases and their biological activities": A short reveiw, Rasayan J. Chem., 11(1), 166-174(2018).
Hamil, A., Khalifa, K. M., Almutaleb, A. A. & Nouradean, M. Q. "Synthesis, characterization and antibacterial activity studies of some transition metal chelates of Mn(II), Ni(II) and Cu(II) with Schiff Base derived from diacetylmonoxime with ophenylenediamine", Advanced Journal of Chemistry-Section A,3(4),524– 533(2020). DOI: 10.33945/SAMI/AJCA. 2020. 4.1
Hamil, A. M. & El-ajaily, M. M. "Synthesis and Physiochemical Investigation of cobalt (II) and nickel (II) complexes of 1-2-[(Z)-2-(3-acetyl-4-hydroxyphenyl)-1-diazenyl]phenyl-1-ethanone", J.Chem.Soc.Pak., 33( 5), 652(2011).
Hamil, A. M. Khalifa, M., AL-Houni, K. A. & El-ajaily, M. M. "Synthesis, spectroscopic investigation and antibacterial activity of Schiff base complexes of cobalt (II) and copper (II) ions", RASAYAN J, Chem, 2(2), 261-266(2009). DOI.org/10.4314/csj.v6i2.7.
Khalifa, M. K., Hamil, A. M., Ali, A. Q., Mohamed, N., Alkhayali, Y. A. & Saad, S. A. "Synthesis, characterization and antibacterial studies of 4- amino-3- hydroxyn-aphthalene-1-sulphoric acid derivate chelates of Cr(III), Mn(II), Co(II) and Cu(II) complexes", Journal of Sebha University-(Pure and Applied Sciences, 15(2),12-24(2016).
Kharadi, G. J. "Thermal decomposition and mass spectra of mixed ligand copper(II) complexes of 1,10-phenanthroline and coumarin derivatives", J. Therm Anal Calorim., 107,651–659(2012). DOI 10.1007/s10973-011-1671-x
Kharadi, G. J., Patel, J. R. & B. Z. Dholakiya, "Antituberculosis, antifungal and thermal activity of mixed ligand transition metal complexes, Applied Organometallic Chemistry, 24 (11), 821-827 (2010). DOI.org/10.1002/aoc.1711
Köylü, M. Z., Ekinci, A. & M. Böyükata, UDC 539.143.43 and H. Temela, "Dynamic 1HNMR studies of Schiff base derivatives, Journal of Applied Spectroscopy, 82(6), 904-909 (2016). DOI.org/10.1007/s10812-016-0202-8
Mandal, D., Haldar, A., Chakraborty P. & Ganguly, R. Synthesis, Characterization, and Structure of Mixed-Ligand Cobalt (II) Complex with N, O Donor Sites, Molbank 2022, M1447, 1-8(2022). DOI.org/10.3390/M1447.
Mane, P. S., Salunke, S. M. & More, B. S. "Synthesis and structural studies of transition metal complexes with bidentate Schiff base derived from 3-acetyl-6-methyl-(2H)-pyran-2,4(3H)-dione", E-Journal of Chemistry, 8(S1), S245-S252(2011).
Ommenya, F. K., Nyawade, E. A., Andala, D. M. & Kinyua, J. "Synthesis, characterization and antibacterial Activity of Schiff Base, 4-Chloro-2-{(E)-[(4-fluorophenyl)imino]methyl}phenol Metal (II) complexes", Journal of Chemistry, Volume 2020, Article ID 1745236, 1-8.
Pal, N., Kumar, M. & Seth, G. "Biological important Ni(II) ternary complexes derived from 2-substituted benzothiazoles and amino acids", E-Journal of Chemistry, 8(3), 1174-1179(2011).
Qamar, N., Sultan, H. , Khan, K. M., Azmat, R., Naz, R., Hameed A. and
Lateef, M.,"8-hydroxyquinoline-Methionine mixed ligands metal complexes:
Preparation and their antioxidant activity", 3058-3061(2019).
Reiss, A., Cioateră, N., Dobritescu, A., Rotaru, M., Carabet,A. C., Parisi, F. Gănescu, A., Dăbuleanu, I., Spînu, C. & Bioactive, P. R. Co(II), Ni(II), and Cu(II) Complexes Containing a Tridentate Sulfathiazole-Based (ONN) Schiff Base, Molecules, 26, 3062, 1-18 (2021). DOI.org/10.3390/molecules26103062
Sabik, A. E., Karabork, M., Ceyhan, G., Tumer, M. & Dıgrak, M. " Polydentate Schiff base ligands and their La(III) complexes: Synthesis, characterization, antibacterial, thermal, and electrochemical properties", International Journal of Inorganic Chemistry,Article ID 791219, 11, 1-13 (2012).DOI.org. 10.1155/ 2012/ 791219
Sani, U. & S. Dailami, A. "Synthesis, Characterization, antimicrobial activity and antioxidant studies of metal(II) complexes of Schiff base derived from 2 –hydroxy - 1- naphthaldehyde and hydrazine monohydrate", ChemSearch Journal, 6(2),35-41(2015). DOI. org/10.4314/csj.v6i2.7
Shaker, S. A. "Preparation and spectral properties of mixed ligand complexes of VO(IV), Ni(II), Zn(II), Pd(II), Cd(II) and Pb(II) with dimethylglyoxime and N-acetylglycine", E-Journal of Chemistry, 7(S1), S580-S586(2010).
Sonmez, M. "Synthesis and characterization of copper(II),nickel(II), cadmium(II), cobalt(II) and zinc(II) complexes with 2-benzoyl-3-hydroxy-1-naphthylamino-3-phenyl-2- propen-1-on", Turk J. Chem., 25, 181–185(2001).
Sumrra, S. H., Ibrahim, M., Ambreen, S., Imran, M., Danish, M. & Rehmani, F. S. "Synthesis, spectral characterization, and biological evaluation of transition metal complexes of bidentate N, O donor Schiff bases", Bioinorganic Chemistry and Applications, Volume, Article ID 812924, 10,1-11(2014). DOI. org/ 10.1155/ 2014/ 812924.
Shyamala, B. S., Lakshmi, P.V.A., & Raju, V. J. T. "Synthesis, antifeedant and insect growth¬regulating activity of N¬(2¬-nitro)-benzylidineaminocoumarin complexes and their physico¬chemical characterization", International Journal of Pharmacy and Pharmaceutical Sciences, 2(4),150-154(2010).
Vairalakshmi, M., Princess, R., Rani, B. K. & Raja, S. J. "Synthesis, structural elucidation, catalytic, antibacterial and antioxidant activities of thiophene derived from mixed ligand metal complexes", J. Chil. Chem. Soc.,63(1), 3844- 3849(2018).
Wankhede, D. S. "Synthesis and characterization of mixed ligand complexes derived from 4-(benzeneazo)salicylaldehyde and 2-amino-4-nitrophenol using transition metal nitrates", Pelagia Research Library Der Chemica Sinica, 6(3):52-58(2015).
