Clinical pattern of psoriasis in patients seen at our private clinic, in Aden, Yemen

Authors

  • Amer Omer Bin Al-Zou Associate Professor, Department of Dermatology, Faculty of Medicine, University of Aden, Yemen

DOI:

https://doi.org/10.37375/sjms.v2i1.1591

Keywords:

pattern,, psoriasis,, Aden, Yemen.

Abstract

Background: Psoriasis is a chronic immune-mediated systemic disease that is influenced by genetic and environmental factors.  Objective: To presents the demographic characteristics, and clinical variants of psoriatic patients.  Materials and methods:  Present work was a retrospective and observational study, conducted in patients of a private clinic of dermatology, in Almansoora, Aden, Yemen. All patients who attended the clinic during the period January 2018 to December 2021 and were diagnosed as psoriasis patients were included in this study.   Data were collected and entered in a computer, and analyzed by using SPSS version 17. Results: The study patients were 168. They were (57.1%) males and (42.9%) females, with a male-to-female ratio of 1.3:1. The age of the patients ranged between 10 to 58 years. The mean age of the patients was 38.2 ± 12.6 years. The age group 41 – 50 had the highest number of patients 54 (32.1%), followed by the age group 31 – 40 years 40 (23.8%) years. The mean duration since the onset of the disease is 6.1 ± 4.6 years. The most common psoriasis type was plaque psoriasis (vulgaris) (65.4%). Family history related to psoriasis was positive among (20.2%) patients.    Diabetes mellitus and hypertriglyceridemia were found equally among the study patients, each one in (9.5%) and arterial hypertension was found in (7.2%) patients. The involvement of nails was observed in (31%) of patients and Koebner phenomena was found in (23.8%) of patients. Conclusion: Psoriasis is predominant in male patients, with a male-to-female ratio of 1.3:1, and the most common psoriasis type was plaque psoriasis.

References

Affandi MA, Khan I, Ngah Saaya N. (2018). Epidemiology and clinical features of adult patients with psoriasis in Malaysia: 10-year review from the Malaysian Psoriasis Registry (2007–2016) Dermatol Res Pract. 2018 April 23;2018:4371471.

Alamri A, Alqahtani R, Alshareef I, et al. (2022). Psoriasis in Saudi Population: Gender Differences in Clinical Characteristics and Quality of Life. Cureus, vol. 14, no. 3, pp. e22892.

Alhumidi AA. (2013). Retrospective 10 years review of 100 patients with psoriasis in the Kingdom of Saudi Arabia (KSA). Am J Res Commun, vol. 8, pp. 114–120.

Al-Qassimi S, AlBrashdi S, Galadari H, Hashim MJ. (2020). Global burden of psoriasis–comparison of regional and global epidemiology, 1990 to 2017. Int J Dermatol, vol. 59, no. 5, pp. 566–571.

Alzeer F, AlOtair H, Aleisa A. (2022). Epidemiology and Cutaneous Manifestations of Psoriasis in Saudi Arabia: A Narrative Review. Clin Cosmet Investig Dermatol, vol. 15, pp. 347-355

Bedi TR. (1995). Clinical profile of psoriasis in North India. Indian J Dermatol Venereol Leprol, vol. 61, no. 4, pp. 202–205.

Boehncke WH, Schon MP. (2015). Psoriasis. Lancet, vol. 386, issue. 9997, pp. 983–994.

Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. (2013). Is the prevalence of psoriasis increasing? A 30–year follow-up of a population–based cohort. Br J Dermatol, vol. 168, pp. 1303–1310.

Dogra A, Arora AK. (2014). Nail psoriasis: the journey so far. Indian J Dermatol, vol. 59, no. 4, pp. 319–333.

Egeberg A, Skov L, Gislason GH, Thyssen JP, Mallbris L. (2017). Incidence and prevalence of psoriasis in Denmark. Acta Derm Venereol, vol. 97, no. (6-7), pp. 808–812.

El-Komy MHM, Mashaly H, Sayed KS, El-Desouky ED, Zaher HA, Rasheed H. (2020). Clinical and epidemiologic features of psoriasis patients in an Egyptian medical center. JAAD Int, vol. 1, no. 2, pp. 81-90.

Fatema F, Ghoshal L, Saha A, Agarwal S, Bandyopadhyay D. (2021). Early-Onset Versus Late-Onset Psoriasis: A Comparative Study of Clinical Variables, Comorbidities, and Association with HLA CW6 in a Tertiary Care Center. Indian J Dermatol, vol. 66, no. 6, pp. 705.

Ferrándiz C, Pujol RM, García-Patos V, Bordas X, Smandía JA. (2002). Psoriasis of early and late onset: a clinical and epidemiologic study from Spain. J Am Acad Dermatol, vol. 46, pp. 867–73.

Friedewald VE, Cather JC, Gelfand JM, et al. (2008). Psoriasis and coronary artery disease. Am J Cardiol, vol. 102, no. 12, pp. 1631-1643.

Gelfand J, Weinstein R, Porter S, et al. (2005). Prevalence and Treatment of Psoriasis in the United Kingdom. Archives of Dermatology, vol. 141, no. 12, pp. 1537-41.

Gibbs S. (1996). Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol, vol. 35, no. 9, pp. 633–639.

Goolam-Mahyoodeen N, Crowther NJ, Pillay L, Snyman T, Toman M, Daya S, et al. (2019). Relationship of Visceral Fat and Adipokines With Cardiometabolic Diseases in Psoriasis. Acta Derm Venereol, vol. 99, no. 13, pp. 1218–1223.

Harden JL, Krueger JG, Bowcock AM. (2015). The immunogenetics of psoriasis: a comprehensive review. J Autoimmun, vol. 64, pp. 66–73.

Henseler T, Christophers E. (1985). Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol, vol. 13, no. 3, pp. 450–456.

Institute for Health Metrics and Evaluation (IHME). (2012).

Global Burden of Disease Study 2010: Results by Cause 1990–2010. Seattle, IHME; 2012. https://doi.org/10.6069/J86D-DZ43

Kurd SK, Gelfand JM. (2009). The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: results from NHANES 2003-2004,” Journal of the American Academy of Dermatology, vol. 60, no. 2, pp. 218–224.

Lønnberg AS, Skov L, Skytthe A, Kyvik KO, Pedersen OB, and Thomsen SF. Smoking and risk for psoriasis: A population-based twin study,” International Journal of Dermatology, vol. 55, no. 2, pp. 72–78, 2016.

Lowes MA, Bowcock AM, Krueger JG. (2007). Pathogenesis and therapy of psoriasis. Nature, vol. 445, no. 7130, pp. 866-873.

Mikrani JA, Shrestha A. (2014). Clinical and epidemiological features of psoriasis in patients visiting Lumbini Medical College. J Lumbini Med Coll, vol. 2, no. 1, pp. 1–3.

Nevitt GJ, Hutchinson PE. Psoriasis in the community: prevalence, severity and patients’ beliefs and attitudes towards the disease. Br J Dermatol, vol. 135, no. 4, pp. 533–537.

Olsen AO, Grjibovski A, Magnus P, Tambs K, and Harris JR. (2005). Psoriasis in Norway as observed in a population-based Norwegian twin panel,” British Journal of Dermatology, vol. 153, no. 2, pp. 346–351.

Pariser D, Schenkel B, Carter C, Farahi K, Brown TM, Ellis CN. Psoriasis Patient Interview Study Group. A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis. J Dermatol Treat. 2016; 27, no. 1, pp. 19–26.

Parisi R, Symmons DPM, Griffiths CEM, Ashcroft DM. (2013). Global epidemiology of psoriasis: a systematic review of incidence and prevalence. Journal of Investigative Dermatology, vol. 133, no. 2, pp. 377–385.

Parisi R, Iskandar IYK, Kontopantelis E, Augustin M, Griffiths CEM, Ashcroft DM. (2020). Global Psoriasis Atlas. National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study. BMJ, v 369:m1590. doi: 10.1136/bmj.m1590.

Rachakonda TD, Schupp CW, Armstrong AW. (2014). Psoriasis prevalence among adults in the United States. Journal of the American Academy of Dermatology, vol. 70, no. 3, pp. 512–516.

Sanclemente G, Mora O, Velez N, Diaz CJ, Quevedo E, Amador J, et al. (2022). Epidemiologic characteristics and burden of psoriasis: A multicenter, cross-sectional study. Medwave, vol. 22, no. 8, pp. 002564

Schons KR, Knob CF, Murussi N, et al. (2014). Nail psoriasis:a review of the literature. An Bras Dermatol, vol. 89, no. 2, pp. 312–317.

Seckin D, Tokgozoglu L, Akkaya S. (1994). Are lipoprotein profile and lipoprotein a levels altered in men with psoriasis? J Am Acad Dermatol, vol. 31, pp. 445–449.

Seminara NM, Abuabara K, Shin DB, et al. (2011). Validity of the Health Improvement Network (THIN) for the study of psoriasis,” British Journal of Dermatology, vol. 164, no. 3, pp. 602–609.

Shajeri MA, Al-Fahaad H. (2014). Psoriasis in children: a study from the southern part of Saudi Arabia. Gulf J Dermatol Venereol, vol. 21, no. 1, pp. 34–37.

Springate DA, Parisi R, Kontopantelis E, Reeves D, Griffiths CEM, and Ashcroft DM. (2017). Incidence, prevalence and mortality of patients with psoriasis: a U.K. population-based cohort study,” British Journal of Dermatology, vol. 176, no. 3, pp. 650–658.

Stern R, Nijsten T, Feldman S, et al. (2004). Psoriasis Is Common, Carries a Substantial Burden Even When Not Extensive, and Is Associated with Widespread Treatment Dissatisfaction. Journal of Investigative Dermatology Symposium Proceedings, vol. 9, no. 2, pp. 136-39.

Valenzuela F, Silva P, Valdés MP, Papp K. (2011). Epidemiology and quality of life of patients with psoriasis in Chile. Actas Dermosifiliogr, vol. 102, pp. 810–816.

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Published

2023-06-30

How to Cite

Bin Al-Zou, A. O. (2023). Clinical pattern of psoriasis in patients seen at our private clinic, in Aden, Yemen . Sirte Journal of Medical Sciences, 2(1), 25–30. https://doi.org/10.37375/sjms.v2i1.1591