The role of High performance liquid chromatography to Identification of rat liver microsomes responsible for the in-vitro metabolite formation of Dipyrone
Abstract
Dipyrone is a non-steroidal anti-inflammatory drug (NSAID), commonly used in the past as a powerful painkiller and fever reducer. It is better known under the brand names Conmel®, Neo-Melubrina®, Magnopyrol®, Prodolina F®, Analgin®, and Novalgin®.
Because of the risk of serious adverse effects, its use is justified only in serious situations where no alternative is available or suitable.
References
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presents the contributor to the main of metabolism of metamizole in rat liver.
