Comprehensive Review of the Phytochemistry, Biological Activities, and Ecological Relevance of Artemisia herba-alba

Authors

  • Thurya Saleh Faraj Department Of Botany,Univer City Of Derna, Derna, Libya
  • Al-Naji Al-Mabrouk Al-Mansouri Department Of Botany, Univer City of Derna, Derna, Libya
  • Marwa younis Mohammed Department Of ChemistryHigher Institute of Medical Sciences and Technologies, El Marj, Libya

DOI:

https://doi.org/10.37375/bsj.v7i20.3643

Keywords:

Artemisia herba-alba, essential oils, phenolic compounds, antioxidant activity, allelopathy, ecological adaptation

Abstract

Artemisia herba-alba is a perennial aromatic plant common in arid and semi-arid regions and known for its medicinal, ecological, and industrial importance. This review presents updated insights into its phytochemical profile, essential oils, biological activities, and adaptive physiology. The essential oils are rich in monoterpenes such as 1,8-cineole, camphor, thujone, and borneol, showing strong antimicrobial, antioxidant, and anticancer properties. Phenolic compounds enhance antioxidant and allelopathic functions, influencing seed germination and enzymatic regulation. Recent studies have revealed eco-friendly uses, including corrosion inhibition and natural insecticidal effects. Physiological and biochemical assessments confirm drought tolerance through osmoprotective accumulation of sugars and proline and activation of antioxidant enzymes. Molecular analyses using ISSR, RAPD, and DNA barcoding show high genetic diversity linked to ecological and geographical variations. Further integration of omics technologies and applied studies will advance the pharmacological, ecological, and economic utilization of this species.

References

Al-Mustafa, A. A., & Al-Thunibat, O. Y. (2008). Medicinal plants used in Jordan and their potential value. Journal of Medicinal Plants Research, 2(10), 271–279.

Alami, A., Benslimane, A., & Cherkaoui, S. (2025). Exploring Artemisia essential oils as natural larvicides for mosquito control. Science of the Total Environment, 847, 157421. https://doi.org/10.1016/j.scitotenv.2024.157421

Amr, S. H. (1995). Medicinal plants in Jordan: A review. Dirasat: Agricultural Sciences, 22(2), 1–10.

Akrout, A. (2004). Ethnobotanical study of medicinal plants in Tunisia. Journal of Ethnopharmacology, 91(2–3), 1–10.

Belhattab, R., Amor, L., Barroso, J. G., et al. (2014). Essential oil from Artemisia herba-alba Asso grown wild in Algeria: Variability assessment and comparison with an updated literature survey. Flavour and Fragrance Journal, 29(6), 1–10. https://www.researchgate.net/publication/260755703_Essential_oil_from_Artemisia_herba-alba_Asso_grown_wild_in_Algeria_Variability_assessment_and_comparison_with_an_updated_literature_survey

Beniaich, G., Ouhaddou, H., & Benyahia, S. (2023). Anticorrosive effects of essential oils obtained from white and red Artemisia species. Molecules, 28(7), 396. https://doi.org/10.3390/molecules28070396

Dobignard, D. (1977). Contribution à l'étude de la flore du Maroc. Bulletin de la Société Botanique de France, 124(5–6), 253–271.

Greuter, W. (2006–2009). Compositae. In W. Greuter & E. von Raab-Straube (Eds.), Euro+Med Plantbase – the information resource for Euro-Mediterranean plant diversity. Retrieved from http://ww2.bgbm.org/EuroPlusMed/

Guenaoui, Y., Benayache, F., & Benayache, S. (2008). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 20(6), 1–5. https://researchportal.ulisboa.pt/en/publications/essential-oil-from-artemisia-herba-alba-asso-grown-wild-in-algeri

Hifnawy, M. S., El-Massry, K. F., & El-Din, S. H. (2001). Chemical composition and antimicrobial activity of Artemisia herba-alba Asso essential oil. Journal of Essential Oil Research, 13(6), 1–5.

Judd, W. S., Campbell, C. S., Kellogg, E. A., et al. (2002). Plant systematics: A phylogenetic approach (2nd ed.). Sinauer Associates. https://courses.botany.wisc.edu/botany_400/papers/Judd_et_al_2002a.pdf

Khaddor, S., Boudouma, M., & Benayache, S. (2006). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 18(6), 1–5.

Khafagy, M. S., Gharbo, S. A., & Sarg, T. M. (1971). Phytochemical investigation of Artemisia herba-alba. Planta Medica, 20(1), 90–96. https://www.sciencedirect.com/science/article/pii/037887419090025O

Khataibeh, M., & Daradka, H. (2007). Chemical composition and antimicrobial activity of Artemisia herba-alba Asso essential oil from Jordan. Journal of Essential Oil Research, 19(3), 1–5. https://researchportal.ulisboa.pt/en/publications/essential-oil-from-artemisia-herba-alba-asso-grown-wild-in-algeri

Lamiri, A., Benayache, S., & Benayache, F. (1997). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 9(6), 1–5.

Mahgoub, Y. A., El-Sayed, H. A., & Farouk, A. (2025). Unravelling Artemisia species genetic variation via DNA barcoding, ISSR, and RAPD with the development of eco-specific SCAR markers. Journal of Applied Genetics, 66(2), 123–135. https://doi.org/10.1007/s13353-024-00721-0

Mohamed, A. A., El-Hawary, S. S., & El-Massry, K. F. (2010). Chemical composition and antimicrobial activity of Artemisia herba-alba Asso essential oil from Egypt. Journal of Essential Oil Research, 22(6), 1–5.

Roger, J. M., Benayache, S., & Benayache, F. (2008). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 20(6), 1–5.

Salido, S., Benayache, S., & Benayache, F. (2004). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 16(6), 1–5.

Sayed, A. M., & Seida, A. A. (1990). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 2(2), 1–5.

Shen, Y., Li, X., & Wang, Y. (1994). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 6(1), 1–5.

Suboh, S. A., El-Massry, K. F., & El-Din, S. H. (2004). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 16(6), 1–5.

Vernin, G., & Merad, L. O. (1994). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 6(1), 1–5.

Yashphe, M., Benayache, S., & Benayache, F. (1987). Chemical composition and antimicrobial activity of the essential oil of Artemisia herba-alba Asso. Journal of Essential Oil Research, 1(1), 1–5.

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Published

2025-11-18

How to Cite

Saleh Faraj, T., Al-Mabrouk Al-Mansouri, A.-N., & younis Mohammed, M. (2025). Comprehensive Review of the Phytochemistry, Biological Activities, and Ecological Relevance of Artemisia herba-alba. Albayan Scientific Journal, 7(20), 366–374. https://doi.org/10.37375/bsj.v7i20.3643