Retrospective Study of Histopathological Patterns of Thyroid Lesions at Sirte Oncology Centre, Central Libya.
DOI:
https://doi.org/10.37375/susj.v16i1.4147الكلمات المفتاحية:
Thyroid Lesions، Patterns، Neoplastic and Non-neoplastic، Libyaالملخص
Background: Thyroid disorders are common worldwide. Thyroid disorders can be neoplastic or non-neoplastic lesions. The author noted that no prior studies on thyroid lesions were undertaken in Sirte City. This study aimed to define the histopathological patterns, frequency, and demographic distribution of non-neoplastic and neoplastic thyroid lesions in thyroidectomy specimens at Sirte Oncology Center. Material and methods: A retrospective cross-sectional study was conducted at pathology department of Sirte Oncology Centre, Sirte, Libya, covering the period from July 2021 to December 2024. Collected data were tabulated and analyzed using SPSS version 26.0 statistical software. Results: Seventy-two thyroidectomy specimens were analyzed with patients aged 20–75 years; females predominated (83.3%). There were 40 (55.6%) neoplastic thyroid lesions, and 32 (44.4%) non-neoplastic. The most common neoplastic lesion was malignant neoplasms (72.5%), predominantly papillary carcinoma (67.5%) followed by benign adenoma (25%). The most frequently reported non-neoplastic thyroid lesions were hyperplastic changes (68.7%), mainly multinodular goiter (65.6%). The most common histological pattern among both neoplastic and non-neoplastic thyroid lesions was papillary carcinoma followed by nodular goiter. Most of thyroid lesions diagnosed in the 41–50-year age group (34.72%) followed by 31–40 years (26.39%) with papillary thyroid carcinoma most common in the former group. Conclusion: Neoplastic lesions outnumber the non-neoplastic lesions in this study. Papillary carcinoma followed by nodular goiter recorded as the most frequent lesions. The current study emphasizes the need for population-based epidemiological research to investigate the true epidemiology of neoplasms in this region and to investigate the demographic and etiological factors.المراجع
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