Emerging of leishmaniasis in Zamzum, Libya.

  • Mohammed A. Dow Department of Family medicine and community health, Faculty of Medicine, Sirte University.
  • Fathi S. Elkasah Department of Dermatology, Faculty of Medicine, Sirte University.
  • Abdulla M. Lahwal 3Department of Infectious disease, Faculty of Medicine, Sirte University.
Keywords: leishmaniasis, Emerging disease, Cutaneous leishmaniasis


A pilot study on leishmaniasis was carried in the outpatient clinic, Zamzam, Libya, from 4 October 2018 to 31 May 2019. A total of 84 patients with cutaneous leishmaniasis (CL) were studied. The duration of the lesions varied from a few days to 3 months. Multiple lesions ranging from one to 21 were present in 78% of cases. Ulcerative lesions were found in 37%, nodulo-ulcerative in 22%, nodular in 30% and others, including infiltrated, fungating and warty lesions, in 3% of patients. The lower limbs were involved in 66%, upper limbs in 36% (Figure. 1), face in 89%, back in 6%, chest in 1%, and abdomen in 2%. Lesions were also found on the ear, scalp, genitalia and mucocutaneous junctions. Lymphatic involvement was present in 9% of the patients, secondary infection in 10%, fever in 12%, and pain in 40% and itching in 72%. Features of diffuse cutaneous leishmaniasis were noted in 3 patients. Slit skin smear was positive for parasites in 67 cases (highly positive in 34 cases). Various therapeutic regimens are discussed. Only patients with severe lesions (approximately 21%) were given 3 to 4 weeks' treatment with intravenous Pentostam, to which all except 4 responded satisfactorily with minimal side effects



Akhlagh A, Salehzadeh A, Zahirnia AH, Davari B. (2019). 10-year trends in epidemiology, diagnosis, and treatment of cutaneous Leishmaniasis in Hamadan Province, West of Iran (2007–2016). Front Public Health. 7:27.

Ashford RW, Schnur LF, Chance ML, Samaan SA, Ahmed HN. (1977). Cutaneous leishmaniasis in the Libyan Arab Republic: preliminary ecological findings. Ann Trop Med Parasitol. 71(3):265-71.

Mohammed MA., Ahmed MS., Eltahir AGk., Maged AA. (2019). "Prevalence of Cutaneous Leishmaniasis in Western Highlands in Yemen", Journal of Tropical Medicine. (2019): 7
Murray HW, Berman JD, Davies CR, Saravia NG. (2005). Advances in leishmaniasis. Lancet. 29 (4):1561-77

Grimaldi G Jr, Tesh RB, McMahon-Pratt D. (1989). A review of the geographic distribution and epidemiology of leishmaniasis in the New World. Am J Trop Med Hyg. 41(6):687-725

Safar AT., Rezvan T., Gholamreza S., Zarichehr V., Abbas T. (2006). Childhood cutaneous leishmaniasis: report of 117 cases from Iran. The Korean J Parasitol.; 44 (4): 355-